Abstract

Metabolism and Epigenetics are intricately linked, playing a key role in development, cancer, immune signaling and aging. This symposium brings together world-leading researchers exploring this nexus. The symposium will focus in particular on how metabolites and metabolic networks impact gene regulation, on recently discovered roles of metabolites in disease and how this open novel therapeutic avenues. We will highlight enabling tools linking metabolites, their localisation within tissues and cells with the regulation of chromatin structure, gene activity and epigenetic inheritance.